Prikaz osnovnih podataka o dokumentu

dc.creatorJakovljević, Aleksandar
dc.creatorDuncan, Henry F.
dc.date.accessioned2021-04-27T11:41:42Z
dc.date.available2021-04-27T11:41:42Z
dc.date.issued2020
dc.identifier.issn1532-3382
dc.identifier.urihttps://smile.stomf.bg.ac.rs/handle/123456789/2582
dc.description.abstractArticle Title and Bibliographic Information: Association between diabetes and the outcome of root canal treatment in adults: an umbrella review. Nagendrababu V, Segura-Egea JJ, Fouad AF, Pulikkotil SJ, Dummer PMH. Int Endod J 2020;53(4):455-66. Subjects or Study Selection The umbrella review was developed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and registered a priori in the PROSPERO database (CRD42019141684). The literature search was conducted using multiple electronic databases (PubMed, EBSCOhost, Cochrane, and Scopus electronic databases) from inception to July 2019. Additional searches were performed using citation mining but without gray literature. This review included systematic reviews with or without meta-analysis, published only in English, and evaluating any root canal treatment outcomes comparing diabetic and nondiabetic patients. All other types of studies (eg, case reports, clinical studies, laboratory studies, animal studies, and narrative reviews) were excluded. Two reviewers independently screened titles and abstracts to identify relevant articles, and a third senior reviewer was consulted in cases of disagreement and doubt. Key Study Factor This umbrella review included 4 systematic reviews with a total of 30 primary studies (case-control, cross-sectional, and prospective longitudinal) that investigated the outcome of root canal treatment in diabetic compared with nondiabetic patients. All included reviews were published between 2016 and 2019. In addition, all included reviews performed quality assessment of the primary included studies, while only two conducted a meta-analysis. Main Outcome Measure The main outcome measure was the prevalence of persistent apical periodontitis, measured radiographically, associated with the clinical outcome of root filled teeth in diabetic compared with nondiabetic patients. A quality assessment of included systematic reviews was completed. Main Results Two out of 4 systematic reviews reported that diabetic patients had a greater prevalence of periapical radiolucencies associated with root filled teeth on radiographs. One of the 4 systematic reviews revealed a relationship between diabetes and increased frequency of loss of root filled teeth. In contrast, one systematic review concluded that there was no overall effect of diabetes on root canal treatment outcome. The quality of each individual systematic review included in the current umbrella review was appraised using "A MeaSurement Tool to Assess systematic Reviews" (AMSTAR) and categorized as "medium". Of the two previous meta-analyses carried out, one reported high heterogeneity of included studies while the other reported low heterogeneity. A meta-analysis was not conducted in this umbrella review. Conclusions Diabetes mellitus is associated with the outcome of conventional nonsurgical root canal treatment and should be considered as an important preoperative prognostic factor; however, high-quality clinical studies with improved control of confounding factors and longer follow-up are required to improve the quality of the primary studies in this area.sr
dc.language.isoensr
dc.publisherElseviersr
dc.rightsrestrictedAccesssr
dc.sourceJournal of Evidence Based Dental Practicesr
dc.subjectDiabetes mellitussr
dc.subjectApical periodontitissr
dc.subjectMeta-analysissr
dc.subjectSystematic reviewsr
dc.subjectUmbrella reviewsr
dc.titleDiabetes Mellitus May Negatively Influence the Outcome of Conventional Nonsurgical Root Canal Treatmentsr
dc.typearticlesr
dc.rights.licenseARRsr
dcterms.abstractДунцан, Хенрy Ф.; Јаковљевић, Aлександар;
dc.rights.holderElsevier Inc.sr
dc.citation.volume20
dc.citation.issue3
dc.citation.spage101467
dc.identifier.wos000577569700011
dc.identifier.doi10.1016/j.jebdp.2020.101467
dc.identifier.pmid32921387
dc.identifier.scopus2-s2.0-85088051118
dc.type.versionpublishedVersionsr


Dokumenti

Thumbnail

Ovaj dokument se pojavljuje u sledećim kolekcijama

Prikaz osnovnih podataka o dokumentu