Comparison of clonidine and epinephrine in lidocaine anaesthesia for lower third molar surgery
Samo za registrovane korisnike
2005
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The admixture of clonidine or epinephrine to lidocaine for inferior alveolar nerve block was studied with regard to onset, duration, intensity of anaesthesia, postoperative analgesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), ST segment depression 1 mm and cardiac arrhythmias. Forty healthy patients (ASA I) received 2 ml 2% lidocaine with clonidine (15 mg/ml; n = 20) or epinephrine (12.5 mg/ml; n = 20) in a doubleblind fashion for lower third molar surgery. Duration and intensity were not different between groups, while onset was significantly different by subjective evaluation. The need for postoperative pain medication was significantly lower in the clonidine group. There was a significant decrease in SBP and MAP in both groups 35 min after administration of anaesthesia compared with basal values, while DBP was significantly lower only in the clonidine group. There was no significant difference in SBP, DBP and MAP be...tween groups. HR was significantly increased in the epinephrine group 5 min after administration of anaesthesia and during surgery compared with the clonidine group and with basal values. The presented data suggest that clonidine could be a useful and safe alternative to epinephrine for intraoral block anaesthesia.
Ključne reči:
lidocaine / clonidine / epinephrine / intraoral block anaesthesiaIzvor:
International Journal of Oral & Maxillofacial Surgery, 2005, 34, 4, 401-406Izdavač:
- Churchill Livingstone, Edinburgh
DOI: 10.1016/j.ijom.2004.06.014
ISSN: 0901-5027
PubMed: 16053850
WoS: 000229449100012
Scopus: 2-s2.0-18244362799
Kolekcije
Institucija/grupa
Stomatološki fakultetTY - JOUR AU - Brković, Božidar AU - Todorović, L AU - Stojić, D. PY - 2005 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1246 AB - The admixture of clonidine or epinephrine to lidocaine for inferior alveolar nerve block was studied with regard to onset, duration, intensity of anaesthesia, postoperative analgesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), ST segment depression 1 mm and cardiac arrhythmias. Forty healthy patients (ASA I) received 2 ml 2% lidocaine with clonidine (15 mg/ml; n = 20) or epinephrine (12.5 mg/ml; n = 20) in a doubleblind fashion for lower third molar surgery. Duration and intensity were not different between groups, while onset was significantly different by subjective evaluation. The need for postoperative pain medication was significantly lower in the clonidine group. There was a significant decrease in SBP and MAP in both groups 35 min after administration of anaesthesia compared with basal values, while DBP was significantly lower only in the clonidine group. There was no significant difference in SBP, DBP and MAP between groups. HR was significantly increased in the epinephrine group 5 min after administration of anaesthesia and during surgery compared with the clonidine group and with basal values. The presented data suggest that clonidine could be a useful and safe alternative to epinephrine for intraoral block anaesthesia. PB - Churchill Livingstone, Edinburgh T2 - International Journal of Oral & Maxillofacial Surgery T1 - Comparison of clonidine and epinephrine in lidocaine anaesthesia for lower third molar surgery VL - 34 IS - 4 SP - 401 EP - 406 DO - 10.1016/j.ijom.2004.06.014 ER -
@article{ author = "Brković, Božidar and Todorović, L and Stojić, D.", year = "2005", abstract = "The admixture of clonidine or epinephrine to lidocaine for inferior alveolar nerve block was studied with regard to onset, duration, intensity of anaesthesia, postoperative analgesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), ST segment depression 1 mm and cardiac arrhythmias. Forty healthy patients (ASA I) received 2 ml 2% lidocaine with clonidine (15 mg/ml; n = 20) or epinephrine (12.5 mg/ml; n = 20) in a doubleblind fashion for lower third molar surgery. Duration and intensity were not different between groups, while onset was significantly different by subjective evaluation. The need for postoperative pain medication was significantly lower in the clonidine group. There was a significant decrease in SBP and MAP in both groups 35 min after administration of anaesthesia compared with basal values, while DBP was significantly lower only in the clonidine group. There was no significant difference in SBP, DBP and MAP between groups. HR was significantly increased in the epinephrine group 5 min after administration of anaesthesia and during surgery compared with the clonidine group and with basal values. The presented data suggest that clonidine could be a useful and safe alternative to epinephrine for intraoral block anaesthesia.", publisher = "Churchill Livingstone, Edinburgh", journal = "International Journal of Oral & Maxillofacial Surgery", title = "Comparison of clonidine and epinephrine in lidocaine anaesthesia for lower third molar surgery", volume = "34", number = "4", pages = "401-406", doi = "10.1016/j.ijom.2004.06.014" }
Brković, B., Todorović, L.,& Stojić, D.. (2005). Comparison of clonidine and epinephrine in lidocaine anaesthesia for lower third molar surgery. in International Journal of Oral & Maxillofacial Surgery Churchill Livingstone, Edinburgh., 34(4), 401-406. https://doi.org/10.1016/j.ijom.2004.06.014
Brković B, Todorović L, Stojić D. Comparison of clonidine and epinephrine in lidocaine anaesthesia for lower third molar surgery. in International Journal of Oral & Maxillofacial Surgery. 2005;34(4):401-406. doi:10.1016/j.ijom.2004.06.014 .
Brković, Božidar, Todorović, L, Stojić, D., "Comparison of clonidine and epinephrine in lidocaine anaesthesia for lower third molar surgery" in International Journal of Oral & Maxillofacial Surgery, 34, no. 4 (2005):401-406, https://doi.org/10.1016/j.ijom.2004.06.014 . .