Biocompatibility of Three Root End Filling Materials
Nema prikaza
Autori
Jovanović, LenaMiljević, Llija
Petrović, Bojan
Marković, Dejan
Kojić, Vesna
Bajkin, Branislav
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Dental materials should be biocompatible, in order to prevent any adverse effects on the surrounding tissue caused by direct contact. The ideal root end filling material must have certain characteristics, including biocompatibility, satisfying marginal sealing quality, ability to permit or induce repair of alveolar bone, promote periapical healing and antimicrobial activity. In this study, the cytotoxicity of different materials (amalgam, MTA and Biodentine) was evaluated on a permanent fibroblast cell lines (MRC-5 and L929). The cytotoxicity of all three types of materials was investigated using standard biocompatibility tests: DET, MIT and agar diffusion test. MU test showed that after 24 and 48 hours in both cell cultures, Biodentine had the largest percentage of citotoxicity. The lowest percentage of cytotoxicity showed MTA in both groups. After 72 h in both cell lines, the highest percentage of cytotoxicity had amalgam. The lowest percentage of cytotoxicity showed MTA in both grou...ps. Observing the results of Agar diffusion test, there was no any discoloration detected, neither lysis of cells under the disc. Biocompatibility tests showed high level of cell compatibility of all three tested materials.
Ključne reči:
Biocompatibility / Root End / MTA / Biodentine / AmalgamIzvor:
Journal of Biomaterials & Tissue Engineering, 2014, 4, 3, 253-257Izdavač:
- Amer Scientific Publishers, Valencia
Finansiranje / projekti:
- Hemijsko i strukturno dizajniranje nanomaterijala za primenu u medicini i inženjerstvu tkiva (RS-172026)
- Modulacija signalnih puteva koji kontrolišu intracelularni energetski balans u terapiji tumora i neuro-imuno-endokrinih poremećaja (RS-41025)
DOI: 10.1166/jbt.2014.1165
ISSN: 2157-9083
WoS: 000336075900013
Scopus: 2-s2.0-84921000692
Kolekcije
Institucija/grupa
Stomatološki fakultetTY - JOUR AU - Jovanović, Lena AU - Miljević, Llija AU - Petrović, Bojan AU - Marković, Dejan AU - Kojić, Vesna AU - Bajkin, Branislav PY - 2014 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1854 AB - Dental materials should be biocompatible, in order to prevent any adverse effects on the surrounding tissue caused by direct contact. The ideal root end filling material must have certain characteristics, including biocompatibility, satisfying marginal sealing quality, ability to permit or induce repair of alveolar bone, promote periapical healing and antimicrobial activity. In this study, the cytotoxicity of different materials (amalgam, MTA and Biodentine) was evaluated on a permanent fibroblast cell lines (MRC-5 and L929). The cytotoxicity of all three types of materials was investigated using standard biocompatibility tests: DET, MIT and agar diffusion test. MU test showed that after 24 and 48 hours in both cell cultures, Biodentine had the largest percentage of citotoxicity. The lowest percentage of cytotoxicity showed MTA in both groups. After 72 h in both cell lines, the highest percentage of cytotoxicity had amalgam. The lowest percentage of cytotoxicity showed MTA in both groups. Observing the results of Agar diffusion test, there was no any discoloration detected, neither lysis of cells under the disc. Biocompatibility tests showed high level of cell compatibility of all three tested materials. PB - Amer Scientific Publishers, Valencia T2 - Journal of Biomaterials & Tissue Engineering T1 - Biocompatibility of Three Root End Filling Materials VL - 4 IS - 3 SP - 253 EP - 257 DO - 10.1166/jbt.2014.1165 ER -
@article{ author = "Jovanović, Lena and Miljević, Llija and Petrović, Bojan and Marković, Dejan and Kojić, Vesna and Bajkin, Branislav", year = "2014", abstract = "Dental materials should be biocompatible, in order to prevent any adverse effects on the surrounding tissue caused by direct contact. The ideal root end filling material must have certain characteristics, including biocompatibility, satisfying marginal sealing quality, ability to permit or induce repair of alveolar bone, promote periapical healing and antimicrobial activity. In this study, the cytotoxicity of different materials (amalgam, MTA and Biodentine) was evaluated on a permanent fibroblast cell lines (MRC-5 and L929). The cytotoxicity of all three types of materials was investigated using standard biocompatibility tests: DET, MIT and agar diffusion test. MU test showed that after 24 and 48 hours in both cell cultures, Biodentine had the largest percentage of citotoxicity. The lowest percentage of cytotoxicity showed MTA in both groups. After 72 h in both cell lines, the highest percentage of cytotoxicity had amalgam. The lowest percentage of cytotoxicity showed MTA in both groups. Observing the results of Agar diffusion test, there was no any discoloration detected, neither lysis of cells under the disc. Biocompatibility tests showed high level of cell compatibility of all three tested materials.", publisher = "Amer Scientific Publishers, Valencia", journal = "Journal of Biomaterials & Tissue Engineering", title = "Biocompatibility of Three Root End Filling Materials", volume = "4", number = "3", pages = "253-257", doi = "10.1166/jbt.2014.1165" }
Jovanović, L., Miljević, L., Petrović, B., Marković, D., Kojić, V.,& Bajkin, B.. (2014). Biocompatibility of Three Root End Filling Materials. in Journal of Biomaterials & Tissue Engineering Amer Scientific Publishers, Valencia., 4(3), 253-257. https://doi.org/10.1166/jbt.2014.1165
Jovanović L, Miljević L, Petrović B, Marković D, Kojić V, Bajkin B. Biocompatibility of Three Root End Filling Materials. in Journal of Biomaterials & Tissue Engineering. 2014;4(3):253-257. doi:10.1166/jbt.2014.1165 .
Jovanović, Lena, Miljević, Llija, Petrović, Bojan, Marković, Dejan, Kojić, Vesna, Bajkin, Branislav, "Biocompatibility of Three Root End Filling Materials" in Journal of Biomaterials & Tissue Engineering, 4, no. 3 (2014):253-257, https://doi.org/10.1166/jbt.2014.1165 . .