Gene polymorphisms in odontogenic keratocysts and ameloblastomas: A systematic review
Само за регистроване кориснике
2021
Чланак у часопису (Објављена верзија)
,
Wiley Periodicals LLC
Метаподаци
Приказ свих података о документуАпстракт
Objectives
The aim of this systematic review was to critically analyze available data on gene polymorphisms in odontogenic keratocysts (OKC) and ameloblastomas, including their possible relationship with clinical and histological features of these lesions.
Materials and Methods
A comprehensive search of Web of Science Scopus, PubMed, Cochrane Central Register of Controlled Trials and EMBASE was conducted using relevant key terms and supplemented by a gray literature search. Quality assessment of included studies was performed using criteria from the Strengthening the Reporting of Genetic Association (STREGA) statement.
Results
Ten studies were included in the final review. Survivin ‐31G/C, interleukin IL‐1α ‐889 C/T, p53 codon 72 G/C, tumor necrosis factor TNF‐α (−308G>A) and its receptor TNF‐R1 (36A>G), glioma‐associated oncogene homolog 1 rs2228224 and matrix metalloproteinase 2 rs243865 gene polymorphisms were reported to be associated with OKC. For ameloblastomas, p53 codo...n 72 G/C, X‐ray repair cross‐complementing protein 1—codons 194 and 399 and matrix metalloproteinase 9 rs3918242 gene polymorphisms were identified as risk factors. It was not possible to establish a relationship between specific polymorphisms and clinical and histological features of investigated lesions.
Conclusions
Several gene polymorphisms might be considered as a risk factor for the development of these lesions. Future studies should investigate whether these polymorphisms might be used to identify patients with increased risk of recurrence or aggressive disease.
Кључне речи:
ameloblastoma / association study / gene polymorphism / keratocystic odontogenic tumor / odontogenic keratocyst / single nucleotide polymorphismИзвор:
Oral Diseases, 2021Издавач:
- Wiley
Финансирање / пројекти:
- Генетичка контрола и молекуларни механизми у малигним, инфламаторним и развојним патологијама орофацијалне регије (RS-MESTD-Basic Research (BR or ON)-175075)
DOI: 10.1111/odi.13865
ISSN: 1354-523X
PubMed: 33793041
Scopus: 2-s2.0-85104069209
Колекције
Институција/група
Stomatološki fakultetTY - JOUR AU - Andrić, Miroslav AU - Jaćimović, Jelena AU - Jakovljević, Aleksandar AU - Nikolić, Nadja AU - Milašin, Jelena PY - 2021 UR - https://smile.stomf.bg.ac.rs/handle/123456789/2578 AB - Objectives The aim of this systematic review was to critically analyze available data on gene polymorphisms in odontogenic keratocysts (OKC) and ameloblastomas, including their possible relationship with clinical and histological features of these lesions. Materials and Methods A comprehensive search of Web of Science Scopus, PubMed, Cochrane Central Register of Controlled Trials and EMBASE was conducted using relevant key terms and supplemented by a gray literature search. Quality assessment of included studies was performed using criteria from the Strengthening the Reporting of Genetic Association (STREGA) statement. Results Ten studies were included in the final review. Survivin ‐31G/C, interleukin IL‐1α ‐889 C/T, p53 codon 72 G/C, tumor necrosis factor TNF‐α (−308G>A) and its receptor TNF‐R1 (36A>G), glioma‐associated oncogene homolog 1 rs2228224 and matrix metalloproteinase 2 rs243865 gene polymorphisms were reported to be associated with OKC. For ameloblastomas, p53 codon 72 G/C, X‐ray repair cross‐complementing protein 1—codons 194 and 399 and matrix metalloproteinase 9 rs3918242 gene polymorphisms were identified as risk factors. It was not possible to establish a relationship between specific polymorphisms and clinical and histological features of investigated lesions. Conclusions Several gene polymorphisms might be considered as a risk factor for the development of these lesions. Future studies should investigate whether these polymorphisms might be used to identify patients with increased risk of recurrence or aggressive disease. PB - Wiley T2 - Oral Diseases T1 - Gene polymorphisms in odontogenic keratocysts and ameloblastomas: A systematic review DO - 10.1111/odi.13865 ER -
@article{ author = "Andrić, Miroslav and Jaćimović, Jelena and Jakovljević, Aleksandar and Nikolić, Nadja and Milašin, Jelena", year = "2021", abstract = "Objectives The aim of this systematic review was to critically analyze available data on gene polymorphisms in odontogenic keratocysts (OKC) and ameloblastomas, including their possible relationship with clinical and histological features of these lesions. Materials and Methods A comprehensive search of Web of Science Scopus, PubMed, Cochrane Central Register of Controlled Trials and EMBASE was conducted using relevant key terms and supplemented by a gray literature search. Quality assessment of included studies was performed using criteria from the Strengthening the Reporting of Genetic Association (STREGA) statement. Results Ten studies were included in the final review. Survivin ‐31G/C, interleukin IL‐1α ‐889 C/T, p53 codon 72 G/C, tumor necrosis factor TNF‐α (−308G>A) and its receptor TNF‐R1 (36A>G), glioma‐associated oncogene homolog 1 rs2228224 and matrix metalloproteinase 2 rs243865 gene polymorphisms were reported to be associated with OKC. For ameloblastomas, p53 codon 72 G/C, X‐ray repair cross‐complementing protein 1—codons 194 and 399 and matrix metalloproteinase 9 rs3918242 gene polymorphisms were identified as risk factors. It was not possible to establish a relationship between specific polymorphisms and clinical and histological features of investigated lesions. Conclusions Several gene polymorphisms might be considered as a risk factor for the development of these lesions. Future studies should investigate whether these polymorphisms might be used to identify patients with increased risk of recurrence or aggressive disease.", publisher = "Wiley", journal = "Oral Diseases", title = "Gene polymorphisms in odontogenic keratocysts and ameloblastomas: A systematic review", doi = "10.1111/odi.13865" }
Andrić, M., Jaćimović, J., Jakovljević, A., Nikolić, N.,& Milašin, J.. (2021). Gene polymorphisms in odontogenic keratocysts and ameloblastomas: A systematic review. in Oral Diseases Wiley.. https://doi.org/10.1111/odi.13865
Andrić M, Jaćimović J, Jakovljević A, Nikolić N, Milašin J. Gene polymorphisms in odontogenic keratocysts and ameloblastomas: A systematic review. in Oral Diseases. 2021;. doi:10.1111/odi.13865 .
Andrić, Miroslav, Jaćimović, Jelena, Jakovljević, Aleksandar, Nikolić, Nadja, Milašin, Jelena, "Gene polymorphisms in odontogenic keratocysts and ameloblastomas: A systematic review" in Oral Diseases (2021), https://doi.org/10.1111/odi.13865 . .