High levels of Paleolithic Y-chromosome lineages characterize Serbia
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2012
Authors
Regueiro, MariaRivera, Luis
Damnjanović, Tatjana
Luković, Ljiljana
Milašin, Jelena
Herrera, Rene J.
Article (Published version)
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Whether present-day European genetic variation and its distribution patterns can be attributed primarily to the initial peopling of Europe by anatomically modern humans during the Paleolithic, or to latter Near Eastern Neolithic input is still the subject of debate. Southeastern Europe has been a crossroads for several cultures since Paleolithic times and the Balkans, specifically, would have been part of the route used by Neolithic farmers to enter Europe. Given its geographic location in the heart of the Balkan Peninsula at the intersection of Central and Southeastern Europe, Serbia represents a key geographical location that may provide insight to elucidate the interactions between indigenous Paleolithic people and agricultural colonists from the Fertile Crescent In this study, we examine, for the first time, the Y-chromosome constitution of the general Serbian population. A total of 103 individuals were sampled and their DNA analyzed for 104 Y-chromosome bi-allelic markers and 17 a...ssociated STR loci. Our results indicate that approximately 58% of Serbian Y-chromosomes (I1-M253, I2a-P37.2 and R1a1a-M198) belong to lineages believed to be pre-Neolithic. On the other hand, the signature of putative Near Eastern Neolithic lineages, including E1b1b1a1-M78, G2a-P15, J1-M267, J2-M172 and R1b1a2-M269 accounts for 39% of the Y-chromosome. Haplogroup frequency distributions in Western and Eastern Europe reveal a spotted landscape of paleolithic Y chromosomes, undermining continental-wide generalizations. Furthermore, an examination of the distribution of Y-chromosome filiations in Europe indicates extreme levels of Paleolithic lineages in a region encompassing Serbia, Bosnia-Herzegovina and Croatia, possibly the result of Neolithic migrations encroaching on Paleolithic populations against the Adriatic Sea.
Keywords:
Y-chromosome / Neolithic transition / Agricultural revolution / Serbia / Y-STRs / Y-SNPsSource:
Gene, 2012, 498, 1, 59-67Publisher:
- Elsevier, Amsterdam
DOI: 10.1016/j.gene.2012.01.030
ISSN: 0378-1119
PubMed: 22310393
WoS: 000302589800009
Scopus: 2-s2.0-84858155635
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Stomatološki fakultetTY - JOUR AU - Regueiro, Maria AU - Rivera, Luis AU - Damnjanović, Tatjana AU - Luković, Ljiljana AU - Milašin, Jelena AU - Herrera, Rene J. PY - 2012 UR - https://smile.stomf.bg.ac.rs/handle/123456789/1745 AB - Whether present-day European genetic variation and its distribution patterns can be attributed primarily to the initial peopling of Europe by anatomically modern humans during the Paleolithic, or to latter Near Eastern Neolithic input is still the subject of debate. Southeastern Europe has been a crossroads for several cultures since Paleolithic times and the Balkans, specifically, would have been part of the route used by Neolithic farmers to enter Europe. Given its geographic location in the heart of the Balkan Peninsula at the intersection of Central and Southeastern Europe, Serbia represents a key geographical location that may provide insight to elucidate the interactions between indigenous Paleolithic people and agricultural colonists from the Fertile Crescent In this study, we examine, for the first time, the Y-chromosome constitution of the general Serbian population. A total of 103 individuals were sampled and their DNA analyzed for 104 Y-chromosome bi-allelic markers and 17 associated STR loci. Our results indicate that approximately 58% of Serbian Y-chromosomes (I1-M253, I2a-P37.2 and R1a1a-M198) belong to lineages believed to be pre-Neolithic. On the other hand, the signature of putative Near Eastern Neolithic lineages, including E1b1b1a1-M78, G2a-P15, J1-M267, J2-M172 and R1b1a2-M269 accounts for 39% of the Y-chromosome. Haplogroup frequency distributions in Western and Eastern Europe reveal a spotted landscape of paleolithic Y chromosomes, undermining continental-wide generalizations. Furthermore, an examination of the distribution of Y-chromosome filiations in Europe indicates extreme levels of Paleolithic lineages in a region encompassing Serbia, Bosnia-Herzegovina and Croatia, possibly the result of Neolithic migrations encroaching on Paleolithic populations against the Adriatic Sea. PB - Elsevier, Amsterdam T2 - Gene T1 - High levels of Paleolithic Y-chromosome lineages characterize Serbia VL - 498 IS - 1 SP - 59 EP - 67 DO - 10.1016/j.gene.2012.01.030 ER -
@article{ author = "Regueiro, Maria and Rivera, Luis and Damnjanović, Tatjana and Luković, Ljiljana and Milašin, Jelena and Herrera, Rene J.", year = "2012", abstract = "Whether present-day European genetic variation and its distribution patterns can be attributed primarily to the initial peopling of Europe by anatomically modern humans during the Paleolithic, or to latter Near Eastern Neolithic input is still the subject of debate. Southeastern Europe has been a crossroads for several cultures since Paleolithic times and the Balkans, specifically, would have been part of the route used by Neolithic farmers to enter Europe. Given its geographic location in the heart of the Balkan Peninsula at the intersection of Central and Southeastern Europe, Serbia represents a key geographical location that may provide insight to elucidate the interactions between indigenous Paleolithic people and agricultural colonists from the Fertile Crescent In this study, we examine, for the first time, the Y-chromosome constitution of the general Serbian population. A total of 103 individuals were sampled and their DNA analyzed for 104 Y-chromosome bi-allelic markers and 17 associated STR loci. Our results indicate that approximately 58% of Serbian Y-chromosomes (I1-M253, I2a-P37.2 and R1a1a-M198) belong to lineages believed to be pre-Neolithic. On the other hand, the signature of putative Near Eastern Neolithic lineages, including E1b1b1a1-M78, G2a-P15, J1-M267, J2-M172 and R1b1a2-M269 accounts for 39% of the Y-chromosome. Haplogroup frequency distributions in Western and Eastern Europe reveal a spotted landscape of paleolithic Y chromosomes, undermining continental-wide generalizations. Furthermore, an examination of the distribution of Y-chromosome filiations in Europe indicates extreme levels of Paleolithic lineages in a region encompassing Serbia, Bosnia-Herzegovina and Croatia, possibly the result of Neolithic migrations encroaching on Paleolithic populations against the Adriatic Sea.", publisher = "Elsevier, Amsterdam", journal = "Gene", title = "High levels of Paleolithic Y-chromosome lineages characterize Serbia", volume = "498", number = "1", pages = "59-67", doi = "10.1016/j.gene.2012.01.030" }
Regueiro, M., Rivera, L., Damnjanović, T., Luković, L., Milašin, J.,& Herrera, R. J.. (2012). High levels of Paleolithic Y-chromosome lineages characterize Serbia. in Gene Elsevier, Amsterdam., 498(1), 59-67. https://doi.org/10.1016/j.gene.2012.01.030
Regueiro M, Rivera L, Damnjanović T, Luković L, Milašin J, Herrera RJ. High levels of Paleolithic Y-chromosome lineages characterize Serbia. in Gene. 2012;498(1):59-67. doi:10.1016/j.gene.2012.01.030 .
Regueiro, Maria, Rivera, Luis, Damnjanović, Tatjana, Luković, Ljiljana, Milašin, Jelena, Herrera, Rene J., "High levels of Paleolithic Y-chromosome lineages characterize Serbia" in Gene, 498, no. 1 (2012):59-67, https://doi.org/10.1016/j.gene.2012.01.030 . .