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Hedgehog signaling pathway and vitamin D receptor gene variants as potential risk factors in odontogenic cystic lesions
(Springer Heidelberg, Heidelberg, 2019)
ObjectivesGenetic variants in the hedgehog signaling pathway and VDR gene are involved in inflammatory responses and neoplastic transformation. Current study investigated whether single-nucleotide polymorphisms in the ...
Trigeminal neuropathic pain development and maintenance in rats are suppressed by a positive modulator of alpha 6 GABA(A) receptors
(Wiley, Hoboken, 2019)
gamma-Aminobutyric acid type A (GABA(A)) receptors containing the alpha 6 subunit are located in trigeminal ganglia, and their reduction by small interfering RNA increases inflammatory temporomandibular and myofascial pain ...
Biological and molecular effects of bromodomain and extra-terminal (BET) inhibitors JQ1, IBET-151, and IBET-762 in OSCC cells
(Wiley, Hoboken, 2019)
Background Despite improvements in oral squamous cell carcinoma (OSCC) management, survival rates remain relatively low and novel anti-neoplastic agents are needed. Bromodomain and extra-terminal (BET) inhibitors proved ...
Association of C35T polymorphism in dihydrofolate reductase gene with toxicity of methotrexate in rheumatoid arthritis patients
(Taylor & Francis Ltd, Abingdon, 2019)
Background: Methotrexate (MTX), a folate analogue, is the most commonly used disease-modifying drug in the treatment of rheumatoid arthritis (RA). However, high interindividual differences in drug response are present among ...
Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives
(Springer Heidelberg, Heidelberg, 2019)
ObjectivesThe study aims to evaluate the effects of non-thermal atmospheric plasma (NTAP) treatments on dentin wetting and surface free energy (SFE) and compare the effects of NTAP treatment, etch-and-rinse, and self-etch ...
Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives
(Springer Heidelberg, Heidelberg, 2019)
ObjectivesThe study aims to evaluate the effects of non-thermal atmospheric plasma (NTAP) treatments on dentin wetting and surface free energy (SFE) and compare the effects of NTAP treatment, etch-and-rinse, and self-etch ...
Notch Signaling Pathway in Apical Periodontitis: Correlation with Bone Resorption Regulators and Proinflammatory Cytokines
(Elsevier Science Inc, New York, 2019)
Introduction: The exact mechanisms of periapical bone resorption have not been fully elucidated. This study aimed to analyze the expression of Notch signaling molecules (Notch2, Jagged1, and Hey1) and proinflammatory ...
Reconstructing the First Metatarsophalangeal Joint of Homo naledi
(Frontiers Media Sa, Lausanne, 2019)
The aim of the present study was to develop a new method to reconstruct damaged metatarsophalangeal joint (MTPJ) of Homo naledi's fossil and to deepen the understanding of the first metatarsal head (FMH) morphological ...
Voronoi Decomposition of Cardiovascular Dependency Structures in Different Ambient Conditions: An Entropy Study
(Mdpi, Basel, 2019)
This paper proposes a method that maps the coupling strength of an arbitrary number of signals D, D >= 2, into a single time series. It is motivated by the inability of multiscale entropy to jointly analyze more than two ...
Association of C35T polymorphism in dihydrofolate reductase gene with toxicity of methotrexate in rheumatoid arthritis patients
(Taylor & Francis Ltd, Abingdon, 2019)
Background: Methotrexate (MTX), a folate analogue, is the most commonly used disease-modifying drug in the treatment of rheumatoid arthritis (RA). However, high interindividual differences in drug response are present among ...