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Immunohistochemical analysis of gamma catenin in Wilms' tumors
dc.creator | Basta-Jovanović, Gordana | |
dc.creator | Gvozdenović, E. | |
dc.creator | Dimitrijević, I. | |
dc.creator | Brašanac, Dimitrije | |
dc.creator | Vučković, Mila | |
dc.creator | Kalezić, Nevena | |
dc.creator | Baralić, I. | |
dc.creator | Radojević-Škodrić, Sanja | |
dc.creator | Arsić, D. | |
dc.date.accessioned | 2020-07-02T12:17:53Z | |
dc.date.available | 2020-07-02T12:17:53Z | |
dc.date.issued | 2008 | |
dc.identifier.issn | 1551-3815 | |
dc.identifier.uri | https://smile.stomf.bg.ac.rs/handle/123456789/1395 | |
dc.description.abstract | The aim of our study was to investigate the expression of γ-catenin in normal kidney and in Wilms' tumor by immunohistochemistry and to correlate the results with tumor stage, histological type, and prognostic group. We investigated 28 cases of Wilms' tumor, 2 Wilms' tumor metastases in lungs, and 1 specimen of normal renal tissue. Expression of γ-catenin was detected in 14 cases. There was a weak inverse relationship between γ-catenin expression and tumor stage. Expression of γ-catenin was detected in various histologic types of Wilms' tumor, but there was no statistically significant correlation, except in cases with diffuse anaplasia that were negative. In 2 metastatic cases and in the case of bilateral Wilms' tumor γ-catenin immunostaining was not observed Our findings suggest an absence of strong correlation between the loss of γ-catenin and unfavorable outcome. | en |
dc.relation | This work was supported by the Ministry of Science, Technology and Development of Serbia. Address correspondence to Dejan Arsic, Children’s Cancer Research Group, Department of Paediatrics, Christchurch School of Medicine and Health Sciences | |
dc.rights | restrictedAccess | |
dc.source | Fetal & Pediatric Pathology | |
dc.subject | γ-catenin | en |
dc.subject | Adhesion molecules | en |
dc.subject | Histological type | en |
dc.subject | Prognostic group | en |
dc.subject | Tumor stage | en |
dc.title | Immunohistochemical analysis of gamma catenin in Wilms' tumors | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Радојевић-Шкодрић, Сања; Баралић, И.; Брашанац, Димитрије; Баста-Јовановић, Гордана; Димитријевић, И.; Вучковић, Мила; Гвозденовић, Е.; Aрсић, Д.; Калезић, Невена; | |
dc.citation.volume | 27 | |
dc.citation.issue | 2 | |
dc.citation.spage | 63 | |
dc.citation.epage | 70 | |
dc.citation.other | 27(2): 63-70 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000256954000002 | |
dc.identifier.doi | 10.1080/15513810802028704 | |
dc.identifier.pmid | 18568994 | |
dc.identifier.scopus | 2-s2.0-45849147671 | |
dc.type.version | publishedVersion |