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Association of C35T polymorphism in dihydrofolate reductase gene with toxicity of methotrexate in rheumatoid arthritis patients
(Taylor & Francis Ltd, Abingdon, 2019)
Background: Methotrexate (MTX), a folate analogue, is the most commonly used disease-modifying drug in the treatment of rheumatoid arthritis (RA). However, high interindividual differences in drug response are present among ...
Implant stability in posterior maxilla: bone-condensing versus bone-drilling: a clinical study
(Mosby-Elsevier, New York, 2011)
Objective. The aim of this clinical trial was to compare primary and secondary stability of implants placed by bone condensing versus the standard drilling technique in the posterior edentulous maxilla. Study design. ...
Association Between the Methylenetetrahydrofolate Reductase Polymorphisms and Risk of Acute Lymphoblastic Leukemia in Serbian Children
(Lippincott Williams & Wilkins, Philadelphia, 2010)
Methylenetetrahydrofolate reductase (MTHFR) regulates the metabolism of folate and methionine, essential components of DNA synthesis and methylation. Polymorphisms in the MTHFR gene have been associated with susceptibility ...
Expression of Matrix Metalloproteinases and Endogenous Inhibitors in Abdominal Aortic Aneurysm and Aortoiliac Occlusive Disease (Syndrome Leriche)
(Charles Univ Prague, First Faculty Medicine, Prague 6, 2017)
Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) play a complex role in the pathogenesis of atherosclerosis. We compared (1) the histopathological findings in patients with abdominal aortic aneurysms ...
The MMP-2 and MMP-9 promoter polymorphisms and susceptibility to salivary gland cancer
(Balkan Union of Oncology (B.U.ON.), 2016)
Purpose: Matrix metalloproteinases (MMPs) are a family of endopeptidases that may play an important role in the development of salivary gland cancer (SGC). MMP-2 and MMP-9, members of the gelatinase protein family, are ...
Relationship between microstructure, cytotoxicity and corrosion properties of a Cu-Al-Ni shape memory alloy
(Elsevier Sci Ltd, Oxford, 2010)
Cu-Al-Ni shape memory alloys (SMAs) have been investigated as materials for medical devices, but their biomedical application is still limited. The aim of this work was to compare the microstructure, corrosion and cytotoxicity ...
Association between miR-21/146a/155 level changes and acute genitourinary radiotoxicity in prostate cancer patients: A pilot study
(Elsevier GmbH, 2019)
Introduction: Nearly sixty percent of patients with prostate cancer (PCa) undergo radiation therapy (RT). During the course of treatment patients may experience normal tissue reactions. It is a well established fact that ...
Herpesviruses viral loads and levels of proinflammatory cytokines in apical periodontitis
(Wiley, Hoboken, 2018)
ObjectivesThis study aimed to analyse Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) viral loads in symptomatic and asymptomatic apical periodontitis lesions, to determine levels of TNF-, IL-1 and IL-6 in these ...
Quantification of structural changes in acute inflammation by fractal dimension, angular second moment and correlation
(Wiley, Hoboken, 2016)
The aim of the study was to examine alteration and possible application of fractal dimension, angular second moment, and correlation for quantification of structural changes in acutely inflamed tissue. Acute inflammation ...
Ontogenetic changes of craniofacial complex in Turner syndrome patients treated with growth hormone
(Springer Heidelberg, Heidelberg, 2013)
The present study assessed changes of craniofacial complex in Turner syndrome (TS) patients treated with growth hormone (GH) during development. The objective was to examine the growth rate and pattern of craniofacial ...